ADVISORS

Eric O’Neill is a Full Professor of Cell and Molecular Biology at the University of Oxford & Adjunct Professor, Systems Biology Ireland, University College Dublin, Ireland.

His research interests lie broadly in the identification of medically relevant biomarkers and treatments; cell and molecular biology; signal transduction; cell signaling; cancer biology; tissue microenvironmental modeling pre-clinical models; originally discovered the hippo signaling pathway (a key pathway of cell fate during development) in cancer; identification of the role those extracellular microvesicles (EVs) in the communication of the cell phenotypes; determination of the relationship between mechanical stress and EVs, influencing stem cell differentiation in bioengineered systems, 3D organoids in vitro, and in pre-clinical in vivo models.

Recently he has establish a spin-out company for high-efficiency biomarker identification.

Jeremy is an NHS Consultant Plastic Surgeon.  He completed clinical and academic training in Edinburgh, Nottingham, Bradford, Sheffield, The Mayo Clinic, Stoke Mandeville, Oxford, Ganga Hospital, and Chelsea and Westminster.

His research focuses on improving how we measure outcomes in hand and plastic surgery and applying this in different scenarios. These include clinical trials and observational studies and in clinical decision-making solutions. To date, he has secured £5.6million of competitive research funding.

He is interested in evidence synthesis, clinical guideline development, and health service policy. He has held an honorary research fellow at Warwick Evidence (University of Warwick), and both a Scholarship and a Fellowship at The National Institute for Health & Care Excellence (NICE). He is also involved in the development and management of the British Society for Surgery of the Hand's  (BSSH) UK Hand Registry (UKHR), and quality improvement in healthcare.

Patricia’s research involves co-designing Medical Devices and Technologies with people who are vulnerable to skin breakdown.  The focus is on using individuals’ experiences of devices and healthcare systems to identify shortfalls and to work with device users, designers, engineers, materials specialists and industry to co-design devices and systems to meet personal needs and the needs of health care providers. This includes co-creating and validating digital patient recorded outcome indicators and platforms for remote patient and clinician monitoring of recovery and deterioration in response to treatment and care, to enable troubleshooting interventions and routine data capture. Evaluation of the performance and costs of novel devices answers critical questions as to how, why, why not devices meet patients’ needs.

  Patricia’s background is in hospice–based clinical nursing. The lack of suitable technologies and systems to care for patients with extensive skin breakdown in tissue viability, palliative and end-of-life care led to pursuing an academic, translational research career at King’s College.