ProMatrix Technology

Towards in vivo tissue engineering

ProMatrix is unlike ANY other Tissue Scaffold

A highly biological scaffold which, when grafted onto a wound bed, creates a new ‘tissue territory’ or 3D framework to guide and support tissue formation.

ProMatrix targets the early phase of wound healing and is designed to provide optimal properties to promote a regenerative type of tissue healing response.

The formation of new tissue naturally starts through the growth of progenitor cells around the wound. ProMatrix supports the migration of these progenitor cells into the scaffold framework, which thus creates the provisional structure for new tissue formation.

Key properties of ProMatrix

• Rapid vascularisation

Supports the rapid formation of blood capillaries within the structure from the patient’s own wound healing cells. Vascularisation integrates this new tissue territory with the body, and accelerates the process of tissue growth.

• Rapid cellularisation

Supports the rapid ingrowth of fibroblast cells into the scaffold structure, together with the formation of new blood capillaries. The 3D scaffold structure organises the cells and provides space for these cells to replicate and build up a new tissue.

• Rapid deposition of new Extra-cellular Matrix

Allows the cells within the scaffold to naturally deposit a permanent Extracellular Matrix, or network of collagen and other tissue proteins which forms the new tissue.

• Scar-free outcome

The scaffold provides the structure which organises ingrowing cells to form new dermal tissue with a normal skin-like structure. This is in contrast to healing by secondary intention which results in build up of scar tissue.